Will Ferrell

Ted (Man with the Yellow Hat) (voice)

Drew Barrymore

Maggie (voice)

David Cross

Junior (voice)

Eugene Levy

Clovis (voice)

Joan Plowright

Ms. Plushbottom (voice)

Dick Van Dyke

Mr. Bloomsberry (voice)

Frank Welker

George (voice)

Ed O'Ross

Ivan (voice)

Michael Chinyamurindi

Edu (voice)

Michael Sorich

"Seen It" Cab Driver (voice)

Billy West

Manager (voice)

Jeff Bennett

Salesman (voice)

Kath Soucie

Animal Control Receptionist (voice)

Clint Howard

Balloon Man (voice)